Acquired Ichthyosis. Hodgkin's Disease

Ichthyosiform mycosis fungoides: a neoplastic acquired ichthyosis.

Sir, Acquired ichthyoses can either reflect an underlying severe disorder or may be an atypical expression of skin diseases such as cutaneous T-cell lymphomas (1). Otherwise, lymphomatous infiltrates in the skin can cause heterogeneous cutaneous symptoms and lesions, which may range from invisible features to massive tumour nodules. Mycosis fungoides is an epidermotropic cutaneous T-cell lympho...

Acquired Ichthyosis Revealing an Underlying Hodgkin ́s Lymphoma

Acquired ichthyosis is a nonhereditary cutaneous disorder characterized by dry, rough skin with scaling that involves significant areas of the body. The disease most commonly manifests in adulthood and usually represents malignancy, especially hematologic disease. We report a 48-year-old woman who presented to the dermatology out-patient clinic because of severe scaling of the skin with a “dirt...

The Hodgkins Fund Prizes

Viral-related RNA in Hodgkins' disease and other human lymphomas.

Molecular hybridization with radioactively labeled DNA complementary to the RNA of the Rauscher leukemia virus was used to probe for homologous RNA in human lymphomas. 22 of 32 specimens contained RNA possessing homology to the RNA of the mouse leukemia virus, but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. Normal adult and fetal tissues fa...

Motor neuron disease and its association with non-Hodgkins lymphoma.

M otor neuron disease (MND) is a neurodegenerative disorder characterized by muscle atrophy, brisk reflexes, spasticity, fasciculation, and atrophy. The onset of the disease is generally insidious. The pathological process may involve the motor cortex, the spinal cord, and the brainstem. 1 Only upper or only lower motor neurons may be affected. The disease may or may not be seen with neoplasms,...